Two men have been stabbed and police are now on the hunt for their armed attacker.

Police and paramedics were called to reports of a stabbing at James Ruse Dr, Clyde in Sydney’s west about 3.40am on Thursday.

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A 54-year-old man was found with a stab wound to the neck and cheek and a 36-year-old man had been assaulted.

Their injuries are not believed to be serious and they were taken to Westmead Hospital in stable conditions.

Police say the men were taking a 28-year-old Tongan national from Villawood to Sydney Airport when the incident occurred.

The man is described as Pacific Islander/Maori in appearance, with a tanned complexion, a large build, about 180cm tall with black hair, dark eyes and is unshaven.

He was wearing a black coat, black track pants and black and white sneakers.

The attacker remains on the run, with police and the dog squad searching the surrounding area.

Anyone with any information is urged to call Crime Stoppers.